
rHep B vaccine (BTG) | |
Type | Mouse antibody Monoclonal |
Introduction | Hepatitis B is one of a few known non-retroviralviruses which employ reverse transcriptionas a part of its replication process. (HIV, a completely unrelated virus, also uses reverse transcription, but it is a retrovirus.) HBV invades the cell by binding to surface receptor and become internalized. The viral core particles then migrate to the hepatocyte nucleus and the partially double-stranded, relaxed circular genomes (RC-DNA) are repaired to form a covalently closed circular DNA (cccDNA), which is the template for viral genomic and sub-genomic RNAs by cellular RNA polymerase II. Of these, the pregenomic RNA (pgRNA is selectively packaged into progeny capsids and is then reverse-transcribed into new RC-DNA. The core can either bud into the endoplasmic reticulum to be enveloped or exported from the cell or recycled back into the genome for conversion to cccDNA. |
Clone | NYRHepB-1 |
Immunogen | rHep B vaccine (BTG) |
Ig Subclass | Mouse IgG1 |
Purification Method | Protein A column. |
Usage | FOR LABORATORY RESEARCH USE ONLY. |
Applications | Direct ELISA, Western Blot, Immuneprecipitation, immunohistochemistry. |
Cat No.: | PTAB1430017 |
Product Name: | rHep B vaccine (BTG) |
Type: | Protein |
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Application: | Capture ELISA paired with clone 3 |
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