Type

Mouse antibody Monoclonal

Introduction

HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes (1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6).

Clone

NYRHepC

Immunogen

Recombinant HCV peptide Mix

Ig Subclass

Mouse IgG1

Purification Method

Protein A column.

Usage

FOR LABORATORY RESEARCH USE ONLY.

Applications

Direct ELISA, Western Blot, Immuneprecipitation, immunohistochemistry.