Human c-myc | |
Type | Mouse Anti Human Monoclonal |
Introduction | c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of c-Myc have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. |
Clone | NYRhc-myc |
Immunogen | Human c-myc |
Ig Subclass | Mouse IgG1 |
Purification Method | Protein A column. |
Usage | FOR LABORATORY RESEARCH USE ONLY. |
Applications | WB, IP |
Cat No.: | PTAB1450023 |
Product Name: | Human c-myc |
Type: | Protein |
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Application: | WB, IP |
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