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  • Name: human MHC Class II (all)
  • Synonyms:
  • Catalogue Number:PTAB1450030
  • Application:FACS staining, Western Blot, Immuneprecipitation.
  • Price: 100ug ¥800.00
  • Number:
  • Concentration:1mg/ml in PBS with 50% Glycerol.
  • Store:-20oC
human MHC Class II (all)

Type

 Mouse Anti Human Monoclonal

 

Introduction

MHC Class II is consists of 2 membrane spanning proteins. Each of these proteins is roughly 30 kDa, and has of two Globular domains, Alpha-1, Alpha-2, Beta-1 and Beta-2. The two regions farthest away from the membrane are alpha-1 and beta-1. The two proteins link without Covalent Bonds. The MHC Class II protein mainly presents peptides, which have been digested from external sources. MHC Class II is normally only expressed by Antigen Presenting Cells (APC) which digest foreign protein. Within the RER the alpha and beta proteins of the molecule, associate with each other, while a third protein called the "invariant chain," is necessary for stabilizing the complex, without it, they will not associate. The MHC-invariant complex is then passed from the RER, into and out of, the Golgi body. It fuses with an Endocytic compartment, where an external protein has been sampled and degraded.

Clone

Mouse Anti Human Monoclonal

Immunogen

human MHC Class II (all)

Ig Subclass

Mouse IgG2a

Purification Method

Protein A column.

 

Usage

FOR LABORATORY RESEARCH USE ONLY.

Applications

FACS staining, Western Blot, Immuneprecipitation.

Cat No.: PTAB1450030
Product Name: human MHC Class II (all)
Type: Protein
Property:
Origin:
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Application: FACS staining, Western Blot, Immuneprecipitation.
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