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  • Name: Activated Human B cells
  • Synonyms:
  • Catalogue Number:PTAB1460040
  • Application:
  • Price: 100ug ¥800.00
  • Number:
  • Concentration:1mg/ml in PBS with 50% Glycerol.
  • Store:-20oC
Activated Human B cells

Type

 

Mouse Anti Human Monoclonal

 

Introduction

CD40 is part of the TNF-receptor superfamily. CD40 is a necessary mediator for vast range of immune and inflammatory responses together with T cell-dependent immunoglobulin class switching, memory B cell growth, and germinal center formation. The transcription factor AKNA regulates the expression of CD40 and its ligand, which is vital for homotypic cell interactions. Adaptor protein TNFR2 interacts with CD40 and serves as a mediator of the signal transduction. The interaction of CD40 and its ligand is crucial for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. CD40 is the receptor for TNFSF5/CD40L.

Clone

hCD40

Immunogen

Activated Human B cells

Ig Subclass

Mouse IgG1

Purification Method

Protein A column.

 

Usage

FOR LABORATORY RESEARCH USE ONLY.

Applications

Cat No.: PTAB1460040
Product Name: Activated Human B cells
Type: Protein
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