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programmed cell death-Ligand 1,PD-L1
  • Name: PD-L1 (程序性死亡受体-配体1)
  • Synonyms: B7-H1
  • Catalogue Number:PTPD001
  • Application:Antibody binding against PD-1 or PD-L1 leads to antitumor immunity.
  • Price: 50ug ¥1000.00 100ug ¥1600.00 1000ug ¥3800.00
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Product Description: PD-L1 is a ligand for program cell death 1 (PD1). PD-L1 suppresses immune response against tumor cells upon binding to PD1 receptor. PD-L1 is expressed on T and B cells, macrophages, dendritic cells, and some nonimmune cells. Antibody binding against PD-1 or PD-L1 leads to antitumor immunity.

 

Synonyms: Program cell death 1 ligand 1, PDCD1 ligand 1

 

Accession #: Q9NZQ7

 

Quality control: Verified by disulfide mapping and Mass Spectrometry analyses.

 

Purity: >95% by SDS-PAGE gel

 

Product Source: PD-L1 was produced in E. Coli cells transformed with human PD-L1 gene. This product is sterile and does not contain any components of animal origin.

 

Formulation: Sterile filtered through a 0.2 micron filter in 20 mM Tris buffer at pH8.

 

Usage: FOR LABORATORY RESEARCH USE ONLY.

 

Storage/Stability: Avoid repeated freeze-thaw cycles. 12 months at -20 C to -80 C. 1 month at 2 C to 8 C.


References:


  1. Hamanishi, Junzo, et al. "Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer." Proceedings of the National Academy of Sciences 104.9 (2007): 3360-3365.

  2. Lin, David Yin-wei, et al. "The PD-1/PD-L1 complex resembles the antigen-binding Fv domains of antibodies and T cell receptors." Proceedings of the National  Academy of Sciences 105.8 (2008): 3011-3016.


Cat No.: PTPD001
Product Name: PD-L1 (程序性死亡受体-配体1)
Type: Protein
Property:
Origin:
Source:
Application: Antibody binding against PD-1 or PD-L1 leads to antitumor immunity.
Formulation:
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