Purified human B-Cells -FITC | |
Type |
Mouse Anti Human Monoclonal |
Introduction | CD21 is expressed strongly on mature B cells, follicular dentritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro. CD21 functions as receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFNalpha. CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation. |
Clone | CD21 is expressed strongly on mature B cells, follicular dentritic cells and weakly on immature thymocytes and T lymphocytes In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells CD21 expression is also gradually lost after stimulation of B cells in vitro CD21 functions as receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFNalpha CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation |
Immunogen | Purified human B-Cells -FITC |
Ig Subclass | Mouse IgG2a |
Purification Method | Protein A column. |
Usage | FOR LABORATORY RESEARCH USE ONLY. |
Applications |
Cat No.: | PTAB1460035 |
Product Name: | Purified human B-Cells -FITC |
Type: | Protein |
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