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  • Name: Purified human B-Cells -FITC
  • Synonyms:
  • Catalogue Number:PTAB1460035
  • Application:
  • Price: 100ug ¥800.00
  • Number:
  • Concentration:1mg/ml in PBS with 50% Glycerol.
  • Store:-20oC
Purified human B-Cells -FITC

Type

 

Mouse Anti Human Monoclonal

 

Introduction

CD21 is expressed strongly on mature B cells, follicular dentritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro. CD21 functions as receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFNalpha. CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation.

Clone

CD21 is expressed strongly on mature B cells, follicular dentritic cells and weakly on immature thymocytes and T lymphocytes In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells CD21 expression is also gradually lost after stimulation of B cells in vitro CD21 functions as receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFNalpha CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation

Immunogen

Purified human B-Cells -FITC

Ig Subclass

Mouse IgG2a

Purification Method

Protein A column.

 

Usage

FOR LABORATORY RESEARCH USE ONLY.

Applications

Cat No.: PTAB1460035
Product Name: Purified human B-Cells -FITC
Type: Protein
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