Purified Mouse LN T cells -biotin | |
Type |
Rat Anti Mouse Monoclonal |
Introduction | CD8 is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 acts as a co-receptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional CD8 is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8 identifies cytotoxic/suppressor t-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of t-cell mediated killing. CD8 alpha chains bind to class-I MHC molecules alpha-3 domains. |
Clone | NYRmCD8 |
Immunogen | Purified Mouse LN T cells -biotin |
Ig Subclass | Rat IgM |
Purification Method | Protein A column. |
Usage |
FOR LABORATORY RESEARCH USE ONLY. |
Applications | |
| Cat No.： | PTAB1470038 |
| Product Name： | Purified Mouse LN T cells -biotin |
| Type： | Protein |
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