Mixture of mouse activated T cells | |
Type |
Hamster Anti Mouse Monoclonal |
Introduction | CTLA-4 is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. |
Clone | RYNmCTLA-4 |
Immunogen | Mixture of mouse activated T cells |
Ig Subclass | Hamster IgG |
Purification Method | Protein A column. |
Usage |
FOR LABORATORY RESEARCH USE ONLY. |
Applications | Blocking antibody |
| Cat No.： | PTAB1480013 |
| Product Name： | Mixture of mouse activated T cells |
| Type： | Protein |
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| Application： | Blocking antibody |
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