CLEC9A (which has also been termed DNGR1) is the most recently characterized receptor from the Dectin-1 cluster and is expressed in many tissues.In peripheral blood, human CLEC9A is found primarily on the surface of BDCA3+ DCs, although this receptor was also detected on small subsets of monocytes and B-cells. CLEC9A may function as an activation receptor, and was capable of internalizing bound antigens via endocytosis and directing them to the endosomal/lysosomal pathway, resulting in enhanced humoral, CD4+ and CD8+ T-cell responses, even in the absence of adjuvant.
Cat No.: | 03-01-2398 |
Product Name: | Monkey CD370 |
Type: | Protein |
Property: | Recombinant Protein |
Origin: | |
Source: | HEK293 |
Application: | ELISA, WB, Immunogen |
Formulation: | Each vial contains 50ug purified protein(1mg/ml) in PBS(pH7.4). |
Purity: | >95% |
Storage: | Store at -80°C, Avoid freeze / thaw cycle. |
Limitation: | For research use only, not for use in diagnostic procedures. |
Note: |